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5. | | FELFILI, J. M.; SILVA JR, M. C.; REZENDE, A. V.; MACHADO, J. W. B.; WALTER, B. M. T.; SILVA, P. E. N. da; HAY, J. D. Analise comparativa da floristica e fitossociologia da vegetacao arborea do Cerrado sensu stricto na Chapada Pratinha-DF, Brasil. Acta Botanica Brasilica, Brasilia, v.6, n.2, p.27-46, 1992. p.27-46 Biblioteca(s): Embrapa Recursos Genéticos e Biotecnologia. |
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6. | | SILVA JUNIOR, M. C.; FELFILI, J. M.; WALTER, B. M. T.; NOGUEIRA, P. E.; REZENDE, A. V.; MORAIS, R.; NOBREGA, M. G. G. Analise da flora arborea de matas de galeria no Distrito Federal: 21 levantamentos. In: RIBEIRO, J. F.; FONSECA, C. E. L. da; SOUSA-SILVA, J. C. (Ed.). Cerrado: caracterizacao e recuperacao de matas de galeria. Planaltina: Embrapa Cerrados, 2001. p.143-191. Biblioteca(s): Embrapa Cerrados; Embrapa Recursos Genéticos e Biotecnologia. |
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8. | | SEABRA, H. F.; ENCINAS, J. I.; FELFILI, J. M. Analise Estrutural da Mata Ciliar do Corrego Capetinga - DF, Habitat de Callithrix Jacchus Penicillata L. Pesquisa Agropecuaria Brasileira, Brasilia, DF, v.26, n.1, p.11-17, jan.1991 Biblioteca(s): Embrapa Unidades Centrais. |
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Registro Completo
Biblioteca(s): |
Embrapa Pecuária Sudeste. |
Data corrente: |
11/12/2019 |
Data da última atualização: |
11/12/2019 |
Tipo da produção científica: |
Artigo em Periódico Indexado |
Circulação/Nível: |
B - 4 |
Autoria: |
BILHASSI, T. B.; GIGLIOTI, R.; OKINO, C. H.; MALAGO JUNIOR, W.; OLIVEIRA, H. N. de; MARCONDES, C. R.; OLIVEIRA, M. C. de S. |
Afiliação: |
Talita Barban Bilhassi, UNESP; Rodrigo Giglioti, UNESP; CINTIA HIROMI OKINO, CPPSE; WILSON MALAGO JUNIOR, CPPSE; Henrique Nunes de Oliveira, UNESP; CINTIA RIGHETTI MARCONDES, CPPSE; MARCIA CRISTINA DE SENA OLIVEIRA, CPPSE. |
Título: |
Differential IL10 mRNA profiles associated to Babesia bovis and B. bigemina infection levels in persistently infected animals. |
Ano de publicação: |
2019 |
Fonte/Imprenta: |
Open Journal of Veterinary Medicine, v. 9, p.161-169, 2019 |
DOI: |
10.4236/ojvm.2019.911014 |
Idioma: |
Inglês |
Conteúdo: |
This work aimed to find quantitative phenotypic traits that can be used to discriminate the levels of resistance/susceptibility to B. bovis and B. bigemina in two groups of cattle presenting the highest (H) or lowest (L) infection levels and Rhipicephalus microplus ticks count. The animals were selected from a previous study of 50 Canchim (5/8 Charolais/zebu) heifers raised in an endemic area for these parasites. These animals were evaluated regarding their TNFα, IL10, IFN-γ, IL12 and iNOS mRNA levels. No differences were found between these groups regarding TNFα, IFN-γ, IL12β or iNOS transcripts. However, the IL10 transcripts were significantly higher in the H group compared to the L group. Moreover, significant correlation coefficients were observed between B. bovis loads and both IL10 and IFN-γ transcripts, while no correlations were found for B. bigemina loads and all tested immune-related transcripts, suggesting that differential IL10 mRNA profiles were closely associated to B. bovis loads. Our results have contributed to a better understanding of the immune responses against Babesia infection, as we demonstrated that the IL10 cytokine levels might also influence or be influenced by parasitemia levels in persistently infected animals |
Palavras-Chave: |
RT-qPCR; Tick. |
Thesagro: |
Carrapato. |
Thesaurus NAL: |
Animal parasites and pests; Cytokines; Gene expression; Parasites; Rhipicephalus microplus; Ticks. |
Categoria do assunto: |
L Ciência Animal e Produtos de Origem Animal |
Marc: |
LEADER 02225naa a2200313 a 4500 001 2116598 005 2019-12-11 008 2019 bl uuuu u00u1 u #d 024 7 $a10.4236/ojvm.2019.911014$2DOI 100 1 $aBILHASSI, T. B. 245 $aDifferential IL10 mRNA profiles associated to Babesia bovis and B. bigemina infection levels in persistently infected animals.$h[electronic resource] 260 $c2019 520 $aThis work aimed to find quantitative phenotypic traits that can be used to discriminate the levels of resistance/susceptibility to B. bovis and B. bigemina in two groups of cattle presenting the highest (H) or lowest (L) infection levels and Rhipicephalus microplus ticks count. The animals were selected from a previous study of 50 Canchim (5/8 Charolais/zebu) heifers raised in an endemic area for these parasites. These animals were evaluated regarding their TNFα, IL10, IFN-γ, IL12 and iNOS mRNA levels. No differences were found between these groups regarding TNFα, IFN-γ, IL12β or iNOS transcripts. However, the IL10 transcripts were significantly higher in the H group compared to the L group. Moreover, significant correlation coefficients were observed between B. bovis loads and both IL10 and IFN-γ transcripts, while no correlations were found for B. bigemina loads and all tested immune-related transcripts, suggesting that differential IL10 mRNA profiles were closely associated to B. bovis loads. Our results have contributed to a better understanding of the immune responses against Babesia infection, as we demonstrated that the IL10 cytokine levels might also influence or be influenced by parasitemia levels in persistently infected animals 650 $aAnimal parasites and pests 650 $aCytokines 650 $aGene expression 650 $aParasites 650 $aRhipicephalus microplus 650 $aTicks 650 $aCarrapato 653 $aRT-qPCR 653 $aTick 700 1 $aGIGLIOTI, R. 700 1 $aOKINO, C. H. 700 1 $aMALAGO JUNIOR, W. 700 1 $aOLIVEIRA, H. N. de 700 1 $aMARCONDES, C. R. 700 1 $aOLIVEIRA, M. C. de S. 773 $tOpen Journal of Veterinary Medicine$gv. 9, p.161-169, 2019
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